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Target
Retinoic acid receptor alpha
Ligand
BDBM50052958
Substrate
n/a
Meas. Tech.
ChEMBL_195187 (CHEMBL802720)
Kd
10000±n/a nM
Citation
 Beard, RL; Colon, DF; Song, TK; Davies, PJ; Kochhar, DM; Chandraratna, RA Synthesis and structure-activity relationships of retinoid X receptor selective diaryl sulfide analogs of retinoic acid. J Med Chem 39:3556-63 (1996) [PubMed]  Article 
Target
Name:
Retinoic acid receptor alpha
Synonyms:
Nr1b1 | RARA_MOUSE | Rara
Type:
PROTEIN
Mol. Mass.:
50742.79
Organism:
Mus musculus
Description:
ChEMBL_195182
Residue:
462
Sequence:
MASNSSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTSLQHQLPVSGYSTPSPATIETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFDVGMSKESVRNDRNKKKKEAPKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDKVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGLDTLSGQSGGGTRDGGGLAPPPGSCSPSLSPSSHRSSPATQSP
  
Inhibitor
Name:
BDBM50052958
Synonyms:
4-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphthalen-2-ylsulfanyl)-benzoic acid | CHEMBL118693
Type:
Small organic molecule
Emp. Form.:
C22H26O2S
Mol. Mass.:
354.506
SMILES:
Cc1cc2c(cc1Sc1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C
Structure:
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