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Target
D(2) dopamine receptor
Ligand
BDBM50054710
Substrate
n/a
Meas. Tech.
ChEMBL_58196 (CHEMBL670364)
IC50
28±n/a nM
Citation
 Norman, MH; Navas, F; Thompson, JB; Rigdon, GC Synthesis and evaluation of heterocyclic carboxamides as potential antipsychotic agents. J Med Chem 39:4692-703 (1997) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DRD2_MOUSE | Dopamine D2 receptor | Dopamine Receptor D2 | Drd2
Type:
Enzyme
Mol. Mass.:
50957.64
Organism:
Mus musculus (Mouse)
Description:
P61168
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50054710
Synonyms:
1,2,3,4-Tetrahydro-quinoline-8-carboxylic acid [4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-amide | CHEMBL356743
Type:
Small organic molecule
Emp. Form.:
C25H31N5OS
Mol. Mass.:
449.612
SMILES:
O=C(NCCCCN1CCN(CC1)c1nsc2ccccc12)c1cccc2CCCNc12
Structure:
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