Target
Cathepsin G
Ligand
BDBM50279770
Substrate
n/a
Meas. Tech.
ChEMBL_45530 (CHEMBL660233)
pH
7.5±n/a
Ki
>15000±n/a nM
Comments
extracted
Citation
 Regan, JMcGarry, DBruno, JGreen, DNewman, JHsu, CYKline, JBarton, JTravis, JChoi, YMVolz, FPauls, HHarrison, RZilberstein, ABen-Sasson, SAChang, M Anionic- and lipophilic-mediated surface binding inhibitors of human leukocyte elastase. J Med Chem 40:3408-22 (1997) [PubMed]  Article 
Target
Name:
Cathepsin G
Synonyms:
CATG_HUMAN | CG | CTSG
Type:
PROTEIN
Mol. Mass.:
28860.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469016
Residue:
255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
  
Inhibitor
Name:
BDBM50279770
Synonyms:
2-{4-benzyloxy-5-[5-benzyloxy-4-(5-benzyloxy-4-{5-benzyloxy-4-[5-benzyloxy-2-carboxymethoxy-4-(2-carboxymethoxy-5-hydroxybenzyl)benzyl]-2-carboxymethoxybenzyl}-2-carboxymethoxybenzyl)-2-carboxymethoxybenzyl]-2-hydroxymethylphenoxy}acetic acid.H2O | CHEMBL267968
Type:
Small organic molecule
Emp. Form.:
C89H80O25
Mol. Mass.:
1549.5725
SMILES:
OCc1cc(OCc2ccccc2)c(Cc2cc(OCc3ccccc3)c(Cc3cc(OCc4ccccc4)c(Cc4cc(OCc5ccccc5)c(Cc5cc(OCc6ccccc6)c(Cc6cc(O)ccc6OCC(O)=O)cc5OCC(O)=O)cc4OCC(O)=O)cc3OCC(O)=O)cc2OCC(O)=O)cc1OCC(O)=O
Structure:
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