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TargetArachidonate 5-lipoxygenase
LigandBDBM50060898
Substrate/Competitorn/a
Meas. Tech.ChEMBL_157766
IC50 3000±n/a nM
Citation Müller, KPrinz, HGawlik, IZiereis, KHuang, HS Simple analogues of anthralin: unusual specificity of structure and antiproliferative activity. J Med Chem40:3773-80 (1997) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Arachidonate 5-lipoxygenase
Name:Arachidonate 5-lipoxygenase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:49994.23
Organism:Bos taurus
Description:ChEMBL_157766
Residue:430
Sequence:
MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE
ELGDIQLIKIEKRKYWFHDDWYLKYITVKTPCGDYIEFPCYRWISGEGEIVLRDGQAKLA
CDDQIHVLKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVL
NYSKAMENLFINRFMHMFQSSWSDFADFEKIFVRISNTISERVMNHWQEDRMFGYQFLNG
CNPVMIQRCLKLPDNLPVTTEMVECSLERQLTLEQEIEQGNIFIVDFKLLDGIDANKTDP
CTLQFLAAPICLLYKNLANKIVPIAIQLNQVPGEENPIFLPSDAKYDWLLAKIWVRSSDF
HVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICEYG
LFDKANATGG
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50060898
NameBDBM50060898
Synonyms:5,8-Dihydroxy-[1,4]naphthoquinone | 5,8-dihydroxy-1,4-dihydronaphthalene-1,4-dione (7a) | 5,8-dihydroxy-1,4-naphthoquinone | CHEMBL274056 | naphthazalin
TypeSmall organic molecule
Emp. Form.C10H6O4
Mol. Mass.190.1522
SMILESOc1ccc(O)c2C(=O)C=CC(=O)c12 |c:9|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a