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Target
Adenosine receptor A1
Ligand
BDBM50062859
Substrate
n/a
Meas. Tech.
ChEMBL_29122 (CHEMBL642256)
Ki
0.286±n/a nM
Citation
 Holschbach, MH; Fein, T; Krummeich, C; Lewis, RG; Wutz, W; Schwabe, U; Unterlugauer, D; Olsson, RA A1 adenosine receptor antagonists as ligands for positron emission tomography (PET) and single-photon emission tomography (SPET). J Med Chem 41:555-63 (1998) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_BOVIN | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36602.99
Organism:
BOVINE
Description:
ADENOSINE 0 BOVINE::P28190
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYMVYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPVDEDAPAERPDD
  
Inhibitor
Name:
BDBM50062859
Synonyms:
8-Cyclopentyl-1-ethoxymethyl-3-propyl-3,7-dihydro-purine-2,6-dione | CHEMBL152294
Type:
Small organic molecule
Emp. Form.:
C16H24N4O3
Mol. Mass.:
320.3868
SMILES:
CCCn1c2nc([nH]c2c(=O)n(COCC)c1=O)C1CCCC1
Structure:
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