Reaction Details Report a problem with these data
Target
Cysteinyl leukotriene receptor 1
Ligand
BDBM50064066
Substrate
n/a
Meas. Tech.
ChEMBL_52208 (CHEMBL664974)
Kd
79±n/a nM
Citation
 Zwaagstra, ME; Timmerman, H; van de Stolpe, AC; de Kanter, FJ; Tamura, M; Wada, Y; Zhang, MQ Synthesis and structure-activity relationships of carboxyflavones as structurally rigid CysLT1 (LTD4) receptor antagonists. J Med Chem 41:1428-38 (1998) [PubMed]  Article 
Target
Name:
Cysteinyl leukotriene receptor 1
Synonyms:
CLTR1_CAVPO | CYSLTR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39007.58
Organism:
GUINEA PIG
Description:
Leukotriene D4 0 GUINEA PIG::Q2NNR5
Residue:
340
Sequence:
MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSAFQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPPQDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIVVTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
  
Inhibitor
Name:
BDBM50064066
Synonyms:
2-[3-(Benzothiazol-2-ylmethoxy)-phenyl]-6-bromo-4-oxo-4H-chromene-8-carboxylic acid | CHEMBL287559
Type:
Small organic molecule
Emp. Form.:
C24H14BrNO5S
Mol. Mass.:
508.341
SMILES:
OC(=O)c1cc(Br)cc2c1oc(cc2=O)-c1cccc(OCc2nc3ccccc3s2)c1
Structure:
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