Reaction Details Report a problem with these data
Target
Cysteinyl leukotriene receptor 1
Ligand
BDBM50064080
Substrate
n/a
Meas. Tech.
ChEMBL_52208 (CHEMBL664974)
Kd
307±n/a nM
Citation
 Zwaagstra, ME; Timmerman, H; van de Stolpe, AC; de Kanter, FJ; Tamura, M; Wada, Y; Zhang, MQ Synthesis and structure-activity relationships of carboxyflavones as structurally rigid CysLT1 (LTD4) receptor antagonists. J Med Chem 41:1428-38 (1998) [PubMed]  Article 
Target
Name:
Cysteinyl leukotriene receptor 1
Synonyms:
CLTR1_CAVPO | CYSLTR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39007.58
Organism:
GUINEA PIG
Description:
Leukotriene D4 0 GUINEA PIG::Q2NNR5
Residue:
340
Sequence:
MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSAFQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPPQDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIVVTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
  
Inhibitor
Name:
BDBM50064080
Synonyms:
2-[3-((E)-2-Quinolin-2-yl-vinyl)-phenyl]-6-(1H-tetrazol-5-yl)-chromen-4-one | CHEMBL33607
Type:
Small organic molecule
Emp. Form.:
C27H17N5O2
Mol. Mass.:
443.4562
SMILES:
O=c1cc(oc2ccc(cc12)-c1nnn[nH]1)-c1cccc(C=Cc2ccc3ccccc3n2)c1 |w:22.25|
Structure:
Search PDB for entries with ligand similarity: