Reaction Details Report a problem with these data
Target
Prolyl 4-hydroxylase
Ligand
BDBM26122
Substrate
n/a
Meas. Tech.
ChEMBL_1840409 (CHEMBL4340708)
IC50
>1000000±n/a nM
Citation
 Langley, GW; Abboud, MI; Lohans, CT; Schofield, CJ Inhibition of a viral prolyl hydroxylase. Bioorg Med Chem 27:2405-2412 (2019) [PubMed]  Article 
Target
Name:
Prolyl 4-hydroxylase
Synonyms:
A085R | Prolyl 4-hydroxylase
Type:
PROTEIN
Mol. Mass.:
27815.10
Organism:
Paramecium bursaria Chlorella virus 1
Description:
ChEMBL_119118
Residue:
242
Sequence:
MTNKFISYNKMETREYLLTILFVIACFMVLNLERREGFETSDRPGVCDGKYYEKIDGFLSDIECDVLINAAIKKGLIKSEVGGATENDPIKLDPKSRNSEQTWFMPGEHEVIDKIQKKTREFLNSKKHCIDKYNFEDVQVARYKPGQYYYHHYDGDDCDDACPKDQRLATLMVYLKAPEEGGGGETDFPTLKTKIKPKKGTSIFFWVADPVTRKLYKETLHAGLPVKSGEKIIANQWIRAVK
  
Inhibitor
Name:
BDBM26122
Synonyms:
(2E)-but-2-enedioic acid | FUMARIC ACID | Fumarate | fumarate, 10
Type:
Small organic molecule
Emp. Form.:
C4H4O4
Mol. Mass.:
116.0722
SMILES:
OC(=O)\C=C\C(O)=O
Structure:
Search PDB for entries with ligand similarity: