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Target
All-trans-retinol dehydrogenase [NAD(+)] ADH4
Ligand
BDBM50064284
Substrate
n/a
Meas. Tech.
ChEMBL_31171 (CHEMBL641136)
Ki
5200000±n/a nM
Citation
 Schindler, JF; Berst, KB; Plapp, BV Inhibition of human alcohol dehydrogenases by formamides. J Med Chem 41:1696-701 (1998) [PubMed]  Article 
Target
Name:
All-trans-retinol dehydrogenase [NAD(+)] ADH4
Synonyms:
ADH2 | ADH4 | ADH4_HUMAN | Alcohol dehydrogenase | Alcohol dehydrogenase class II
Type:
PROTEIN
Mol. Mass.:
40228.36
Organism:
Homo sapiens (Human)
Description:
ChEMBL_31171
Residue:
380
Sequence:
MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKSVRTILIF
  
Inhibitor
Name:
BDBM50064284
Synonyms:
CHEMBL49963 | N-Cyclopropyl-formamide
Type:
Small organic molecule
Emp. Form.:
C4H7NO
Mol. Mass.:
85.1045
SMILES:
O=CNC1CC1
Structure:
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