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Target
All-trans-retinol dehydrogenase [NAD(+)] ADH1B
Ligand
BDBM50064274
Substrate
n/a
Meas. Tech.
ChEMBL_31169 (CHEMBL641134)
Ki
1700±n/a nM
Citation
 Schindler, JF; Berst, KB; Plapp, BV Inhibition of human alcohol dehydrogenases by formamides. J Med Chem 41:1696-701 (1998) [PubMed]  Article 
Target
Name:
All-trans-retinol dehydrogenase [NAD(+)] ADH1B
Synonyms:
ADH1B | ADH1B_HUMAN | ADH2 | Alcohol dehydrogenase | Alcohol dehydrogenase beta chain
Type:
PROTEIN
Mol. Mass.:
39864.68
Organism:
Homo sapiens (Human)
Description:
ChEMBL_31169
Residue:
375
Sequence:
MSTAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTVLTF
  
Inhibitor
Name:
BDBM50064274
Synonyms:
CHEMBL48122 | N-(1-Methyl-heptyl)-formamide
Type:
Small organic molecule
Emp. Form.:
C9H19NO
Mol. Mass.:
157.2533
SMILES:
CCCCCCC(C)NC=O
Structure:
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