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Target
5-hydroxytryptamine receptor 1B
Ligand
BDBM50064815
Substrate
n/a
Meas. Tech.
ChEMBL_1350 (CHEMBL616535)
Ki
5785±n/a nM
Citation
 Law, H; Dukat, M; Teitler, M; Lee, DK; Mazzocco, L; Kamboj, R; Rampersad, V; Prisinzano, T; Glennon, RA Benzylimidazolines as h5-HT1B/1D serotonin receptor ligands: a structure-affinity investigation. J Med Chem 41:2243-51 (1998) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1B
Synonyms:
5-HT-1B | 5-HT-1D-beta | 5-HT1B | 5-hydroxytryptamine receptor 1B (5-HT1B) | 5HT1B_HUMAN | HTR1B | HTR1DB | S12 | Serotonin (5-HT) receptor | Serotonin 1D beta receptor | Serotonin Receptor 1B
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
43579.17
Organism:
Homo sapiens (Human)
Description:
Receptor binding assays were performed using human clone stably expressed in CHO cells
Residue:
390
Sequence:
MEEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRILKQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTS
  
Inhibitor
Name:
BDBM50064815
Synonyms:
3-(4,5-Dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-phenol | CHEMBL309162
Type:
Small organic molecule
Emp. Form.:
C12H16N2O
Mol. Mass.:
204.2682
SMILES:
Cc1ccc(O)c(C)c1CC1=NCCN1 |t:11|
Structure:
Search PDB for entries with ligand similarity: