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Target
Neuropeptide Y receptor type 1
Ligand
BDBM50065472
Substrate
n/a
Meas. Tech.
ChEMBL_143830 (CHEMBL748714)
Ki
980.0±n/a nM
Citation
 Zarrinmayeh, H; Nunes, AM; Ornstein, PL; Zimmerman, DM; Arnold, MB; Schober, DA; Gackenheimer, SL; Bruns, RF; Hipskind, PA; Britton, TC; Cantrell, BE; Gehlert, DR Synthesis and evaluation of a series of novel 2-[(4-chlorophenoxy)methyl]benzimidazoles as selective neuropeptide Y Y1 receptor antagonists. J Med Chem 41:2709-19 (1998) [PubMed]  Article 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM50065472
Synonyms:
2-(4-Chloro-phenoxymethyl)-1-(3-piperidin-4-yl-propyl)-1H-benzoimidazole | CHEMBL90605
Type:
Small organic molecule
Emp. Form.:
C22H26ClN3O
Mol. Mass.:
383.914
SMILES:
Clc1ccc(OCc2nc3ccccc3n2CCCC2CCNCC2)cc1
Structure:
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