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Target
D(3) dopamine receptor
Ligand
BDBM50512795
Substrate
n/a
Meas. Tech.
ChEMBL_1850351 (CHEMBL4350892)
Ki
3.8±n/a nM
Citation
 Chen, PJ; Taylor, M; Griffin, SA; Amani, A; Hayatshahi, H; Korzekwa, K; Ye, M; Mach, RH; Liu, J; Luedtke, RR; Gordon, JC; Blass, BE Design, synthesis, and evaluation of N-(4-(4-phenyl piperazin-1-yl)butyl)-4-(thiophen-3-yl)benzamides as selective dopamine D Bioorg Med Chem Lett 29:2690-2694 (2019) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50512795
Synonyms:
CHEMBL4438037
Type:
Small organic molecule
Emp. Form.:
C25H27Cl2N3OS
Mol. Mass.:
488.472
SMILES:
Clc1ccc(N2CCN(CCCCNC(=O)c3ccc(cc3)-c3ccsc3)CC2)c(Cl)c1
Structure:
Search PDB for entries with ligand similarity: