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Target
Metabotropic glutamate receptor 6
Ligand
BDBM50069348
Substrate
n/a
Meas. Tech.
ChEBML_104457
EC50
>1000000±n/a nM
Citation
 Kozikowski, AP; Steensma, D; Varasi, M; Pshenichkin, S; Surina, E; Wroblewski, JT alpha-substituted quisqualic acid analogs: new metabotropic glutamate receptor group II selective antagonists. Bioorg Med Chem Lett 8:447-52 (1999) [PubMed]  Article 
Target
Name:
Metabotropic glutamate receptor 6
Synonyms:
GRM6_RAT | Gprc1f | Grm6 | Metabotropic glutamate receptor | Metabotropic glutamate receptor 6 (mGlu6) | Mglur6 | mGlu6 | metabotropic glutamate 6
Type:
Enzyme
Mol. Mass.:
95095.82
Organism:
Rattus norvegicus (Rat)
Description:
P35349
Residue:
871
Sequence:
MGRLPVLLLWLAWWLSQAGIACGAGSVRLAGGLTLGGLFPVHARGAAGRACGALKKEQGVHRLEAMLYALDRVNADPELLPGVRLGARLLDTCSRDTYALEQALSFVQALIRGRGDGDEASVRCPGGVPPLRSAPPERVVAVVGASASSVSIMVANVLRLFAIPQISYASTAPELSDSTRYDFFSRVVPPDSYQAQAMVDIVRALGWNYVSTLASEGNYGESGVEAFVQISREAGGVCIAQSIKIPREPKPGEFHKVIRRLMETPNARGIIIFANEDDIRRVLEATRQANLTGHFLWVGSDSWGSKISPILNLEEEAVGAITILPKRASIDGFDQYFMTRSLENNRRNIWFAEFWEENFNCKLTSSGGQSDDSTRKCTGEERIGQDSAYEQEGKVQFVIDAVYAIAHALHSMHQALCPGHTGLCPAMEPTDGRTLLHYIRAVRFNGSAGTPVMFNENGDAPGRYDIFQYQATNGSASSGGYQAVGQWAEALRLDMEVLRWSGDPHEVPPSQCSLPCGPGERKKMVKGVPCCWHCEACDGYRFQVDEFTCEACPGDMRPTPNHTGCRPTPVVRLTWSSPWAALPLLLAVLGIMATTTIMATFMRHNDTPIVRASGRELSYVLLTGIFLIYAITFLMVAEPCAAICAARRLLLGLGTTLSYSALLTKTNRIYRIFEQGKRSVTPPPFISPTSQLVITFGLTSLQVVGVIAWLGAQPPHSVIDYEEQRTVDPEQARGVLKCDMSDLSLIGCLGYSLLLMVTCTVYAIKARGVPETFNEAKPIGFTMYTTCIIWLAFVPIFFGTAQSAEKIYIQTTTLTVSLSLSASVSLGMLYVPKTYVILFHPEQNVQKRKRSLKKTSTMAAPPQNENAEDAK
  
Inhibitor
Name:
BDBM50069348
Synonyms:
(S)-2-Amino-3-(3,5-dioxo-[1,2,4]oxadiazolidin-2-yl)-2-methyl-propionic acid | CHEMBL138515
Type:
Small organic molecule
Emp. Form.:
C6H9N3O5
Mol. Mass.:
203.1528
SMILES:
C[C@](N)(Cn1oc(=O)[nH]c1=O)C(O)=O
Structure:
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