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Target
5-hydroxytryptamine receptor 1A
Ligand
BDBM50070518
Substrate
n/a
Meas. Tech.
ChEBML_1576
Ki
525±n/a nM
Citation
 Belliotti, TR; Brink, WA; Kesten, SR; Rubin, JR; Wustrow, DJ; Zoski, KT; Whetzel, SZ; Corbin, AE; Pugsley, TA; Heffner, TG; Wise, LD Isoindolinone enantiomers having affinity for the dopamine D4 receptor. Bioorg Med Chem Lett 8:1499-502 (1999) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1A
Synonyms:
5-HT1A | 5-hydroxytryptamine receptor 1A | 5-hydroxytryptamine receptor 1A (5HT1A) | 5HT1A_MOUSE | Gpcr18 | Htr1a | Serotonin 1a (5-HT1a) receptor
Type:
Enzyme
Mol. Mass.:
46192.09
Organism:
Mus musculus (Mouse)
Description:
Q64264
Residue:
421
Sequence:
MDMFSLGQGNNTTTSLEPFGTGGNDTGLSNVTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSNPNECTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKKGAGTSFGTSSAPPPKKSLNGQPGSGDCRRSAENRAVGTPCANGAVRQGEDDATLEVIEVHRVGNSKGHLPLPSESGATSYVPACLERKNERTAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPELLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCR
  
Inhibitor
Name:
BDBM50070518
Synonyms:
(R)-3-{2-[4-(3,4-Dimethyl-phenyl)-piperazin-1-yl]-ethyl}-2,3-dihydro-isoindol-1-one | CHEMBL35093 | PD-172939
Type:
Small organic molecule
Emp. Form.:
C22H27N3O
Mol. Mass.:
349.4693
SMILES:
Cc1ccc(cc1C)N1CCN(CC[C@H]2NC(=O)c3ccccc23)CC1
Structure:
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