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TargetThyrotropin-releasing hormone receptor
LigandBDBM50072394
Substrate/Competitorn/a
Meas. Tech.ChEMBL_210510
Ki 23±n/a nM
Citation Chu, WPerlman, JHGershengorn, MCMoeller, KD Thyrotropin releasing hormone analogs: a building block approach to the construction of tetracyclic peptidomimetics. Bioorg Med Chem Lett8:3093-6 (1999) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Thyrotropin-releasing hormone receptor
Name:Thyrotropin-releasing hormone receptor
Synonyms:TRH-R | Thyroliberin receptor | thyrotropin-releasing hormone R1
Type:Enzyme Catalytic Domain
Mol. Mass.:44568.52
Organism:MOUSE
Description:thyrotropin-releasing hormone R1 TRHR MOUSE::P21761
Residue:393
Sequence:
MENDTVSEMNQTELQPQAAVALEYQVVTILLVVIICGLGIVGNIMVVLVVMRTKHMRTPT
NCYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFT
IERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKNAVVVSCG
YKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKMWKNDSIH
QNKNLNLNATNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENW
FLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKAANYSVALNYSVIKES
DRFSTELEDITVTDTYVSTTKVSFDDTCLASEN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50072394
n/a
NameBDBM50072394
Synonyms:1-[3-(1H-4-imidazolyl)-2-(5-oxotetrahydro-1H-2-pyrrolylcarboxamido)propanoyl]tetrahydro-1H-2-pyrrolecarboxamide | A-38579 | ABBOTT-38579 | PROTIRELIN
TypeSmall organic molecule
Emp. Form.C16H22N6O4
Mol. Mass.362.3837
SMILESNC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCC(=O)N1 |r|
Structure
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