Reaction Details Report a problem with these data
Target
N-acetyllactosaminide alpha-1,3-galactosyltransferase
Ligand
BDBM50072690
Substrate
n/a
Meas. Tech.
ChEMBL_218064 (CHEMBL821936)
Ki
104000±n/a nM
Citation
 Chung, SJ; Takayama, S; Wong, CH Acceptor substrate-based selective inhibition of galactosyltransferases. Bioorg Med Chem Lett 8:3359-64 (1999) [PubMed]  Article 
Target
Name:
N-acetyllactosaminide alpha-1,3-galactosyltransferase
Synonyms:
GGTA1 | GGTA1_PIG
Type:
PROTEIN
Mol. Mass.:
43759.32
Organism:
Sus scrofa
Description:
ChEMBL_218064
Residue:
371
Sequence:
MNVKGRVVLSMLLVSTVMVVFWEYINSPEGSLFWIYQSKNPEVGSSAQRGWWFPSWFNNGTHSYHEEEDAIGNEKEQRKEDNRGELPLVDWFNPEKRPEVVTITRWKAPVVWEGTYNRAVLDNYYAKQKITVGLTVFAVGRYIEHYLEEFLISANTYFMVGHKVIFYIMVDDISRMPLIELGPLRSFKVFEIKSEKRWQDISMMRMKTIGEHILAHIQHEVDFLFCMDVDQVFQNNFGVETLGQSVAQLQAWWYKAHPDEFTYERRKESAAYIPFGQGDFYYHAAIFGGTPTQVLNITQECFKGILQDKENDIEAEWHDESHLNKYFLLNKPTKILSPEYCWDYHIGMSVDIRIVKIAWQKKEYNLVRNNI
  
Inhibitor
Name:
BDBM50072690
Synonyms:
CHEMBL326048 | N-[5-(4-Amino-3,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-4-hydroxy-6-hydroxymethyl-2-methoxy-tetrahydro-pyran-3-yl]-acetamide
Type:
Small organic molecule
Emp. Form.:
C15H28N2O10
Mol. Mass.:
396.3902
SMILES:
COC1OC(CO)C(OC2OC(CO)C(O)C(N)C2O)C(O)C1NC(C)=O
Structure:
Search PDB for entries with ligand similarity: