Reaction Details Report a problem with these data
Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50073251
Substrate
n/a
Meas. Tech.
ChEBML_157700
Ki
0.620000±n/a nM
Citation
 Randad, RS; Lubkowska, L; Eissenstat, MA; Gulnik, SV; Yu, B; Bhat, TN; Clanton, DJ; House, T; Stinson, SF; Erickson, JW Unsymmetric nonpeptidic HIV protease inhibitors containing anthranilamide as a P2' ligand. Bioorg Med Chem Lett 8:3537-42 (1999) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50073251
Synonyms:
CHEMBL118396 | {2-[(1S,3S,4S)-1-Benzyl-3-hydroxy-5-phenyl-4-(thiazol-4-ylmethoxycarbonylamino)-pentylcarbamoyl]-phenyl}-carbamic acid pyridin-2-ylmethyl ester
Type:
Small organic molecule
Emp. Form.:
C37H37N5O6S
Mol. Mass.:
679.785
SMILES:
O[C@@H](C[C@H](Cc1ccccc1)NC(=O)c1ccccc1NC(=O)OCc1ccccn1)[C@H](Cc1ccccc1)NC(=O)OCc1cscn1
Structure:
Search PDB for entries with ligand similarity: