Reaction Details Report a problem with these data
Target
Thromboxane A2 receptor
Ligand
BDBM50075093
Substrate
n/a
Meas. Tech.
ChEBML_225590
IC50
36±n/a nM
Citation
 Shinozaki, K; Sato, H; Iwakuma, T; Sato, R; Kurimoto, T; Yoshida, K Synthesis and thromboxane A2 antagonistic activity activity of indane derivatives. Bioorg Med Chem Lett 9:401-6 (1999) [PubMed]  Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
TA2R_RAT | TXA2/PGH2 | Tbxa2r | Thromboxane A2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36943.05
Organism:
RAT
Description:
Thromboxane A2 TBXA2R RAT::P34978
Residue:
341
Sequence:
MWLNSTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRSSFLALLCGLVLTDFLGLLVTGAVVASQHAALLDWRATDPGCRLCHFMGAAMVFFGLCPLLLGAAMAAERFVGITRPFSRPAATSRRAWATVGLVWVGAGTLGLLPLLGLGRYSVQYPGSWCFLTLGAERGDVAFGLMFALLGSVSVGLSLLLNTVSVATLCRVYHAREATQRPRDCEVEMMVQLVGIMVVATVCWMPLLVFILQTLLQTLPVMSPSGQLLRTTERQLLIYLRVATWNQILDPWVYILFRRSVLRRLHPRFTSQLQAVSLHSPPTQAMLSGP
  
Inhibitor
Name:
BDBM50075093
Synonyms:
CHEMBL130377 | Sodium; 5-{2-[(4-chloro-benzenesulfonylamino)-methyl]-indan-5-yl}-pentanoate
Type:
Small organic molecule
Emp. Form.:
C21H23ClNO4S
Mol. Mass.:
420.93
SMILES:
[O-]C(=O)CCCCc1ccc2CC(CNS(=O)(=O)c3ccc(Cl)cc3)Cc2c1
Structure:
Search PDB for entries with ligand similarity: