Reaction Details Report a problem with these data
Target
Chymotrypsin-like elastase family member 2A
Ligand
BDBM50075117
Substrate
n/a
Meas. Tech.
ChEBML_158076
IC50
1900±n/a nM
Citation
 Iijima, K; Katada, J; Hayashi, Y Symmetrical anhydride-type serine protease inhibitors: structure-activity relationship studies of human chymase inhibitors. Bioorg Med Chem Lett 9:413-8 (1999) [PubMed]  Article 
Target
Name:
Chymotrypsin-like elastase family member 2A
Synonyms:
CEL2A_PIG | CELA2A | ELA2 | ELA2A | Elastase 2A | Elastase-2 | Elastase-2A | Pancreatic elastase
Type:
PROTEIN
Mol. Mass.:
28705.23
Organism:
Sus scrofa
Description:
ChEMBL_156951
Residue:
269
Sequence:
MIRALLLSTLVAGALSCGLPANLPQLPRVVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRHSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAGTILPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMICAGGDGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINSVIANN
  
Inhibitor
Name:
BDBM50075117
Synonyms:
2-phenylcarboxamidopropanoic anhydride | CHEMBL134440
Type:
Small organic molecule
Emp. Form.:
C20H20N2O5
Mol. Mass.:
368.3832
SMILES:
O=C(CCNC(=O)c1ccccc1)OC(=O)CCNC(=O)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: