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Target5-hydroxytryptamine receptor 1D (5HT1D)
LigandBDBM50076428
Substrate/Competitorn/a
Meas. Tech.ChEMBL_3532
Ki 1±n/a nM
Citation Lang, LJagoda, ESchmall, BVuong, BKAdams, HRNelson, DLCarson, REEckelman, WC Development of fluorine-18-labeled 5-HT1A antagonists. J Med Chem42:1576-86 (1999) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 1D (5HT1D)
Name:5-hydroxytryptamine receptor 1D (5HT1D)
Synonyms:Serotonin 1d (5-HT1d) receptor
Type:Enzyme
Mol. Mass.:41605.88
Organism:Mus musculus (Mouse)
Description:Q61224
Residue:374
Sequence:
MSPPNQSLEGLPQEASNRSLNVTGAWDPEVLQALRISLVVVLSVITLATVLSNAFVLTTI
LLTKKLHTPANYLIGSLATTDLLVSILVMPISIAYTTTRTWNFGQILCDIWVSSDITCCT
ASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAAVWIISICISIPPLFWRQATAHE
EMSDCLVNTSQISYTIYSTCGAFYIPSILLIILYGRIYVAARSRILNPPSLYGKRFTTAQ
LITGSAGSSLCSLNPSLHESHTHTVGSPLFFNQVKIKLADSILERKRISAARERKATKTL
GIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPVIYTVFNEDF
RQAFQKVVHFRKIS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50076428
NameBDBM50076428
Synonyms:4-Fluoro-cyclohexanecarboxylic acid {2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-pyridin-2-yl-amide | CHEMBL38413
TypeSmall organic molecule
Emp. Form.C25H33FN4O2
Mol. Mass.440.5535
SMILESCOc1ccccc1N1CCN(CCN(C(=O)C2CCC(F)CC2)c2ccccn2)CC1 |(2.32,-7.79,;3.65,-8.56,;3.63,-10.1,;2.31,-10.86,;2.31,-12.41,;3.63,-13.18,;4.99,-12.41,;4.99,-10.87,;6.3,-10.12,;7.65,-10.89,;8.99,-10.12,;8.96,-8.58,;10.31,-7.82,;11.65,-8.58,;12.96,-7.82,;14.31,-8.58,;14.31,-10.13,;15.63,-7.82,;16.96,-8.58,;18.94,-8.27,;19.49,-9.96,;21.03,-9.96,;18.27,-9.22,;16.18,-9.51,;12.96,-6.27,;11.65,-5.51,;11.65,-3.96,;12.96,-3.19,;14.31,-3.96,;14.31,-5.51,;7.65,-7.81,;6.32,-8.58,)|
Structure
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