Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
Target5-hydroxytryptamine receptor 1D (5HT1D)
LigandBDBM50076429
Substrate/Competitorn/a
Meas. Tech.ChEMBL_3532
Ki 4±n/a nM
Citation Lang, LJagoda, ESchmall, BVuong, BKAdams, HRNelson, DLCarson, REEckelman, WC Development of fluorine-18-labeled 5-HT1A antagonists. J Med Chem42:1576-86 (1999) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 1D (5HT1D)
Name:5-hydroxytryptamine receptor 1D (5HT1D)
Synonyms:Serotonin 1d (5-HT1d) receptor
Type:Enzyme
Mol. Mass.:41605.88
Organism:Mus musculus (Mouse)
Description:Q61224
Residue:374
Sequence:
MSPPNQSLEGLPQEASNRSLNVTGAWDPEVLQALRISLVVVLSVITLATVLSNAFVLTTI
LLTKKLHTPANYLIGSLATTDLLVSILVMPISIAYTTTRTWNFGQILCDIWVSSDITCCT
ASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAAVWIISICISIPPLFWRQATAHE
EMSDCLVNTSQISYTIYSTCGAFYIPSILLIILYGRIYVAARSRILNPPSLYGKRFTTAQ
LITGSAGSSLCSLNPSLHESHTHTVGSPLFFNQVKIKLADSILERKRISAARERKATKTL
GIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPVIYTVFNEDF
RQAFQKVVHFRKIS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50076429
NameBDBM50076429
Synonyms:4-Fluoro-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-3-methyl-N-pyridin-2-yl-benzamide | CHEMBL1910243 | CHEMBL43297
TypeSmall organic molecule
Emp. Form.C26H29FN4O2
Mol. Mass.448.5325
SMILESCOc1ccccc1N1CCN(CCN(C(=O)c2ccc(F)c(C)c2)c2ccccn2)CC1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a