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Target
Beta-1 adrenergic receptor
Ligand
BDBM50077647
Substrate
n/a
Meas. Tech.
ChEBML_37401
Kd
120±n/a nM
Citation
 Suzuki, H; Shindo, K; Ueno, A; Miura, T; Takei, M; Sakakibara, M; Fukamachi, H; Tanaka, J; Higa, T S1319: a novel beta2-andrenoceptor agonist from a marine sponge Dysidea sp. Bioorg Med Chem Lett 9:1361-4 (1999) [PubMed]  Article 
Target
Name:
Beta-1 adrenergic receptor
Synonyms:
ADRB1 | ADRB1R | ADRB1_HUMAN | B1AR | Beta-1 adrenoceptor | adrenergic Beta1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
51338.40
Organism:
Homo sapiens (Human)
Description:
P08588
Residue:
477
Sequence:
MGAGVLVLGASEPGNLSSAAPLPDGAATAARLLVPASPPASLLPPASESPEPLSQQWTAGMGLLMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVCTVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPSPSPVPAPAPPPGPPRPAAAAATAPLANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRELVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAARRRHATHGDRPRASGCLARPGPPPSPGAASDDDDDDVVGATPPARLLEPWAGCNGGAAADSDSSLDEPCRPGFASESKV
  
Inhibitor
Name:
BDBM50077647
Synonyms:
4-Hydroxy-7-(1-hydroxy-2-methylamino-ethyl)-3H-benzothiazol-2-one | 4-hydroxy-7-(1-hydroxy-2-(methylamino)ethyl)benzo[d]thiazol-2(3H)-one | CHEMBL29141
Type:
Small organic molecule
Emp. Form.:
C10H12N2O3S
Mol. Mass.:
240.279
SMILES:
CNCC(O)c1ccc(O)c2[nH]c(=O)sc12
Structure:
Search PDB for entries with ligand similarity: