Target
H2-K region expressed gene 2, rat orthologue
Ligand
BDBM50079846
Substrate
n/a
Meas. Tech.
ChEMBL_103873 (CHEMBL712990)
IC50
160±n/a nM
Citation
 Jones, ABActon, JJAdams, ADYuen, WNichols, EASchwartz, CDWicker, LSHermes, JD Tetrapeptide derived inhibitors of complexation of a class II MHC: fully unnatural ligands. Bioorg Med Chem Lett 9:2115-8 (1999) [PubMed]  Article 
Target
Name:
H2-K region expressed gene 2, rat orthologue
Synonyms:
MHC class II | MHC class II region expressed gene KE2, isoform CRA_a
Type:
PROTEIN
Mol. Mass.:
14499.39
Organism:
Rattus norvegicus
Description:
ChEMBL_10342
Residue:
127
Sequence:
MAELIQKKLQGEVEKYQQLQKDLSKSMSGRQKLEAQLTENNIVKEELALLDGSNVVFKLLGPVLVKQELGEARATVGKRLDYITAEIKRYESQLRDLERQSEQQRETLAQLQQEFQRAQNAKAPGKA
  
Inhibitor
Name:
BDBM50079846
Synonyms:
CHEMBL63598 | N-Butyl-N'-{(S)-2-[(R)-3-(3-cyclohexyl-propylamino)-3-(3-hydroxy-propyl)-2-oxo-pyrrolidin-1-yl]-pentanoyl}-hydrazinecarboxylic acid ethyl ester
Type:
Small organic molecule
Emp. Form.:
C28H52N4O5
Mol. Mass.:
524.7363
SMILES:
CCCCN(NC(=O)[C@H](CCC)N1CC[C@@](CCCO)(NCCCC2CCCCC2)C1=O)C(=O)OCC
Structure:
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