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Target
Retinoic acid receptor RXR-beta
Ligand
BDBM50080526
Substrate
n/a
Meas. Tech.
ChEBML_197086
EC50
33±n/a nM
Citation
 Dhar, A; Liu, S; Klucik, J; Berlin, KD; Madler, MM; Lu, S; Ivey, RT; Zacheis, D; Brown, CW; Nelson, EC; Birckbichler, PJ; Benbrook, DM Synthesis, structure-activity relationships, and RARgamma-ligand interactions of nitrogen heteroarotinoids. J Med Chem 42:3602-14 (1999) [PubMed]  Article 
Target
Name:
Retinoic acid receptor RXR-beta
Synonyms:
Nr2b2 | RXRB_MOUSE | Retinoid X receptor beta | Rxrb
Type:
PROTEIN
Mol. Mass.:
55877.78
Organism:
Mus musculus
Description:
ChEMBL_196588
Residue:
520
Sequence:
MSWATRPPFLPPRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAGEQQALEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLSQGIRPSSPPGPPLTPSAPPPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGDGAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGATGGGGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPGEVEILREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
  
Inhibitor
Name:
BDBM50080526
Synonyms:
1,4,4-Trimethyl-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid 4-ethoxycarbonyl-phenyl ester | CHEMBL422607
Type:
Small organic molecule
Emp. Form.:
C22H25NO4
Mol. Mass.:
367.4382
SMILES:
CCOC(=O)c1ccc(OC(=O)c2ccc3N(C)CCC(C)(C)c3c2)cc1
Structure:
Search PDB for entries with ligand similarity: