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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50082396
Substrate
n/a
Meas. Tech.
ChEBML_79472
Ki
0.240000±n/a nM
Citation
 Patel, M; Rodgers, JD; McHugh, RJ; Johnson, BL; Cordova, BC; Klabe, RM; Bacheler, LT; Erickson-Viitanen, S; Ko, SS Unsymmetrical cyclic ureas as HIV-1 protease inhibitors: novel biaryl indazoles as P2/P2' substituents. Bioorg Med Chem Lett 9:3217-20 (1999) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50082396
Synonyms:
(4R,5S,6S,7R)-1-(3-Amino-benzyl)-4,7-dibenzyl-5,6-dihydroxy-3-[3-(3-methoxy-phenyl)-1H-indazol-5-ylmethyl]-[1,3]diazepan-2-one | CHEMBL321669
Type:
Small organic molecule
Emp. Form.:
C41H41N5O4
Mol. Mass.:
667.7953
SMILES:
COc1cccc(c1)-c1n[nH]c2ccc(CN3[C@H](Cc4ccccc4)[C@H](O)[C@@H](O)[C@@H](Cc4ccccc4)N(Cc4cccc(N)c4)C3=O)cc12
Structure:
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