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TargetSerotonin (5-HT) receptor
LigandBDBM50060429
Substrate/Competitorn/a
Meas. Tech.ChEMBL_2079
IC50>10000±n/a nM
Citation Russell, MGMatassa, VGPengilley, RRvan Niel, MBSohal, BWatt, APHitzel, LBeer, MSStanton, JABroughton, HBCastro, JL 3-[3-(Piperidin-1-yl)propyl]indoles as highly selective h5-HT(1D) receptor agonists. J Med Chem42:4981-5001 (2000) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Serotonin (5-HT) receptor
Name:Serotonin (5-HT) receptor
Synonyms:5-HT-1F | 5-HT1F | 5-hydroxytryptamine receptor 1F | HTR1F | Serotonin 1f (5-HT1f) receptor | Serotonin receptor 1F
Type:Enzyme Catalytic Domain
Mol. Mass.:41724.68
Organism:Homo sapiens (Human)
Description:5-HT1F HTR1F HUMAN::P30939
Residue:366
Sequence:
MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANY
LICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALD
RYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIV
STIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKS
VSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILG
AFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQK
LVRCRC
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50060429
NameBDBM50060429
Synonyms:(R)-2-(4-Fluoro-phenyl)-2-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-ethanol | CHEMBL313714
TypeSmall organic molecule
Emp. Form.C26H31FN6O
Mol. Mass.462.5623
SMILESOC[C@H](NC1CCN(CCCc2c[nH]c3ccc(cc23)-n2cnnc2)CC1)c1ccc(F)cc1
Structure
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n/a