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Target
Cannabinoid receptor 1
Ligand
BDBM50083845
Substrate
n/a
Meas. Tech.
ChEMBL_46821 (CHEMBL657225)
Kd
11±n/a nM
Citation
 Keimowitz, AR; Martin, BR; Razdan, RK; Crocker, PJ; Mascarella, SW; Thomas, BF QSAR analysis of Delta(8)-THC analogues: relationship of side-chain conformation to cannabinoid receptor affinity and pharmacological potency. J Med Chem 43:59-70 (2000) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50083845
Synonyms:
6,6,9-Trimethyl-3-oct-4-enyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol | CHEMBL159872
Type:
Small organic molecule
Emp. Form.:
C24H34O2
Mol. Mass.:
354.5256
SMILES:
CCC\C=C\CCCc1cc(O)c2C3CC(C)=CCC3C(C)(C)Oc2c1 |c:16|
Structure:
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