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Target
Cysteinyl leukotriene receptor 1
Ligand
BDBM50084814
Substrate
n/a
Meas. Tech.
ChEMBL_52222 (CHEMBL663972)
Ki
1.5±n/a nM
Citation
 Palomer, A; Pascual, J; Cabré, F; García, ML; Mauleón, D Derivation of pharmacophore and CoMFA models for leukotriene D(4) receptor antagonists of the quinolinyl(bridged)aryl series. J Med Chem 43:392-400 (2000) [PubMed]  Article 
Target
Name:
Cysteinyl leukotriene receptor 1
Synonyms:
CLTR1_CAVPO | CYSLTR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39007.58
Organism:
GUINEA PIG
Description:
Leukotriene D4 0 GUINEA PIG::Q2NNR5
Residue:
340
Sequence:
MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSAFQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPPQDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIVVTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
  
Inhibitor
Name:
BDBM50084814
Synonyms:
4-(4-(7-(quinolin-2-ylmethoxy)-2-naphthamido)phenyl)butanoic acid | 4-(4-{[7-(Quinolin-2-ylmethoxy)-naphthalene-2-carbonyl]-amino}-phenyl)-butyric acid | CHEMBL131611
Type:
Small organic molecule
Emp. Form.:
C31H26N2O4
Mol. Mass.:
490.5491
SMILES:
OC(=O)CCCc1ccc(NC(=O)c2ccc3ccc(OCc4ccc5ccccc5n4)cc3c2)cc1
Structure:
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