Reaction Details Report a problem with these data
Target
4-aminobutyrate aminotransferase, mitochondrial
Ligand
BDBM50085241
Substrate
n/a
Meas. Tech.
ChEMBL_70672 (CHEMBL679310)
Ki
4200000±n/a nM
Citation
 Qiu, J; Silverman, RB A new class of conformationally rigid analogues of 4-amino-5-halopentanoic acids, potent inactivators of gamma-aminobutyric acid aminotransferase. J Med Chem 43:706-20 (2000) [PubMed]  Article 
Target
Name:
4-aminobutyrate aminotransferase, mitochondrial
Synonyms:
(S)-3-amino-2-methylpropionate transaminase | 2.6.1.19 | 2.6.1.22 | 4-aminobutyrate aminotransferase, mitochondrial | ABAT | GABA aminotransferase | GABA transaminase | GABA-AT | GABA-T | GABAT | GABT_PIG | Gamma-amino-N-butyrate transaminase | L-AIBAT
Type:
n/a
Mol. Mass.:
56633.06
Organism:
Sus scrofa
Description:
n/a
Residue:
500
Sequence:
MASVLLTRRLACSFRHNHRLLVPGWRHISQAAAKVDVEFDYDGPLMKTEVPGPRSRELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSIPIGYSHPALVKLVQQPQNVSTFINRPALGILPPENFVEKLRESLLSVAPKGMSQLITMACGSCSNENAFKTIFMWYRSKERGQSAFSKEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDISRKHGCAFLVDEVQTGGGSTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLSNAAHAGKVLLTGLLDLQARYPQFISRVRGRGTFCSFDTPDESIRNKLISIARNKGVMLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK
  
Inhibitor
Name:
BDBM50085241
Synonyms:
3-Amino-2,4-dibromo-cyclopentanecarboxylic acid | CHEMBL164086
Type:
Small organic molecule
Emp. Form.:
C6H9Br2NO2
Mol. Mass.:
286.949
SMILES:
N[C@@H]1[C@@H](Br)C[C@@H]([C@H]1Br)C(O)=O
Structure:
Search PDB for entries with ligand similarity: