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TargetDopamine receptor D2L/neurotensin receptor NTS1
LigandBDBM50086637
Substrate/Competitorn/a
Meas. Tech.ChEBML_144283
IC50 1.3±n/a nM
Citation Lundquist, JTBüllesbach, EEDix, TA Synthesis of neurotensin(9-13) analogues exhibiting enhanced human neurotensin receptor binding affinities. Bioorg Med Chem Lett10:453-5 (2000) [PubMed]  Article
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Dopamine receptor D2L/neurotensin receptor NTS1
Name:Dopamine receptor D2L/neurotensin receptor NTS1
Synonyms:Neurotensin receptor 1 | neurotensin receptor type 1
Type:PROTEIN
Mol. Mass.:46278.89
Organism:Homo sapiens (Human)
Description:ChEMBL_1453811
Residue:418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDI
YSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAM
PVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLM
SRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVN
TFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRH
GVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTIN
PILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
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BDBM50086637
NameBDBM50086637
Synonyms:(S)-2-{(2S,3S)-2-[(S)-2-({(S)-1-[(S)-5-Amino-2-((S)-2,5-diamino-pentanoylamino)-pentanoyl]-pyrrolidine-2-carbonyl}-amino)-3-(4-hydroxy-phenyl)-propionylamino]-3-methyl-pentanoylamino}-4-methyl-pentanoic acid | CHEMBL138970
TypeSmall organic molecule
Emp. Form.C36H60N8O8
Mol. Mass.732.9104
SMILESCC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN)NC(=O)[C@@H](N)CCCN)C(=O)N[C@@H](CC(C)C)C(O)=O
Structure
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