| Reaction Details |
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 | Report a problem with these data |
| Target | Retinoid receptor |
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| Ligand | BDBM31883 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_196318 |
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| IC50 | 0.500000±n/a nM |
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| Citation |  Kikuchi, K; Hibi, S; Yoshimura, H; Tai, K; Hida, T; Tokuhara, N; Yamauchi, T; Nagai, M Novel retinoic acid receptor alpha agonists: syntheses and evaluation of pyrazole derivatives. Bioorg Med Chem Lett10:619-22 (2000) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinoid receptor |
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| Name: | Retinoic acid receptor RXR-alpha/gamma |
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| Synonyms: | Nuclear receptor subfamily 1 group B member 3 | RAR-gamma | Retinoic acid receptor gamma |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50345.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1458016 |
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| Residue: | 454 |
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| Sequence: | MATNKERLFAAGALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMAS
LSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQK
NMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSY
ELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIK
IVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMH
NAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEA
LRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPE
MFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
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| BDBM31883 |
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| Name | BDBM31883 |
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| Synonyms: | 9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC ACID | AT-RA | Atralin | CHEMBL38 | MLS000028588 | SMR000058245 | TRETINOIN | Vitamin A acid | [3H]RA | [3H]Retinoic acid | [3H]Vitamin A acid | [3H]tretinoin | all-trans retinoic acid | cid_444795 |
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| Type | radiolabeled ligand |
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| Emp. Form. | C20H28O2 |
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| Mol. Mass. | 300.4351 |
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| SMILES | C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O |c:4| |
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| Structure |  |
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| n/a |
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