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TargetAMP deaminase 2
LigandBDBM50087326
Substrate/Competitorn/a
Meas. Tech.ChEMBL_28868
Ki 53000±n/a nM
Citation Bookser, BCKasibhatla, SRAppleman, JRErion, MD AMP deaminase inhibitors. 2. Initial discovery of a non-nucleotide transition-state inhibitor series. J Med Chem43:1495-507 (2000) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
AMP deaminase 2
Name:AMP deaminase 2
Synonyms:AMP deaminase 2 | AMP deaminase 2 (hAMPD2)
Type:Protein
Mol. Mass.:100694.77
Organism:Homo sapiens (Human)
Description:n/a
Residue:879
Sequence:
MRNRGQGLFRLRSRCFLHQSLPLGAGRRKGLDVAEPGPSRCRSDSPAVAAVVPAMASYPS
GSGKPKAKYPFKKRASLQASTAAPEARGGLGAPPLQSARSLPGPAPCLKHFPLDLRTSMD
GKCKEIAEELFTRSLAESELRSAPYEFPEESPIEQLEERRQRLERQISQDVKLEPDILLR
AKQDFLKTDSDSDLQLYKEQGEGQGDRSLRERDVLEREFQRVTISGEEKCGVPFTDLLDA
AKSVVRALFIREKYMALSLQSFCPTTRRYLQQLAEKPLETRTYEQGPDTPVSADAPVHPP
ALEQHPYEHCEPSTMPGDLGLGLRMVRGVVHVYTRREPDEHCSEVELPYPDLQEFVADVN
VLMALIINGPIKSFCYRRLQYLSSKFQMHVLLNEMKELAAQKKVPHRDFYNIRKVDTHIH
ASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNLTAYDLSVDTLDVHAD
RNTFHRFDKFNAKYNPIGESVLREIFIKTDNRVSGKYFAHIIKEVMSDLEESKYQNAELR
LSIYGRSRDEWDKLARWAVMHRVHSPNVRWLVQVPRLFDVYRTKGQLANFQEMLENIFLP
LFEATVHPASHPELHLFLEHVDGFDSVDDESKPENHVFNLESPLPEAWVEEDNPPYAYYL
YYTFANMAMLNHLRRQRGFHTFVLRPHCGEAGPIHHLVSAFMLAENISHGLLLRKAPVLQ
YLYYLAQIGIAMSPLSNNSLFLSYHRNPLPEYLSRGLMVSLSTDDPLQFHFTKEPLMEEY
SIATQVWKLSSCDMCELARNSVLMSGFSHKVKSHWLGPNYTKEGPEGNDIRRTNVPDIRV
GYRYETLCQELALITQAVQSEMLETIPEEAGITMSPGPQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50087326
NameBDBM50087326
Synonyms:3-(4-Hydroxy-butyl)-3,6,7,8-tetrahydro-imidazo[4,5-d][1,3]diazepin-8-ol | CHEMBL37531
TypeSmall organic molecule
Emp. Form.C10H16N4O2
Mol. Mass.224.2596
SMILESOCCCCn1cnc2C(O)CNC=Nc12 |c:13|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a