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Target
Beta-2 adrenergic receptor
Ligand
BDBM50087516
Substrate
n/a
Meas. Tech.
ChEMBL_38610 (CHEMBL652293)
Ki
27000±n/a nM
Citation
 Lu, SF; Herbert, B; Haufe, G; Laue, KW; Padgett, WL; Oshunleti, O; Daly, JW; Kirk, KL Syntheses of (R)- and (S)-2- and 6-fluoronorepinephrine and (R)- and (S)-2- and 6-fluoroepinephrine: effect of stereochemistry on fluorine-induced adrenergic selectivities. J Med Chem 43:1611-9 (2000) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2_CANLF
Type:
PROTEIN
Mol. Mass.:
46593.67
Organism:
Canis familiaris
Description:
ChEMBL_56504
Residue:
415
Sequence:
MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM50087516
Synonyms:
(S)4-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-diol | CHEMBL40796
Type:
Small organic molecule
Emp. Form.:
C8H10FNO3
Mol. Mass.:
187.1683
SMILES:
NC[C@@H](O)c1ccc(O)c(O)c1F
Structure:
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