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Target
Glutathione S-transferase A2
Ligand
BDBM50088968
Substrate
n/a
Meas. Tech.
ChEBML_72327
IC50
90000±n/a nM
Citation
 Brophy, PM; Campbell, AM; van Eldik, AJ; Teesdale-Spittle, PH; Liebau, E; Wang, MF Beta-carbonyl substituted glutathione conjugates as inhibitors Of O. volvulus GST2. Bioorg Med Chem Lett 10:979-81 (2000) [PubMed]  Article 
Target
Name:
Glutathione S-transferase A2
Synonyms:
GST class-alpha member 2 | GST-gamma | GST2 | GSTA2 | GSTA2-2 | GSTA2_HUMAN | GTH2 | HA subunit 2
Type:
PROTEIN
Mol. Mass.:
25667.17
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799590
Residue:
222
Sequence:
MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF
  
Inhibitor
Name:
BDBM50088968
Synonyms:
2-Amino-4-[1-(carboxymethyl-carbamoyl)-2-(1-methyl-3-oxo-pentylsulfanyl)-ethylcarbamoyl]-butyric acid | CHEMBL426936
Type:
Small organic molecule
Emp. Form.:
C16H27N3O7S
Mol. Mass.:
405.466
SMILES:
CCC(=O)CC(C)SCC(NC(=O)CCC(N)C(O)=O)C(=O)NCC(O)=O
Structure:
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