Reaction Details Report a problem with these data
Target
4-hydroxyphenylpyruvate dioxygenase
Ligand
BDBM50089165
Substrate
n/a
Meas. Tech.
ChEBML_543
IC50
30±n/a nM
Citation
 Lin, SW; Lin, YL; Lin, TC; Yang, DY Discovery of a potent, non-triketone type inhibitor of 4-hydroxyphenylpyruvate dioxygenase. Bioorg Med Chem Lett 10:1297-8 (2000) [PubMed]  Article 
Target
Name:
4-hydroxyphenylpyruvate dioxygenase
Synonyms:
HPD | HPPD_PIG
Type:
PROTEIN
Mol. Mass.:
45064.25
Organism:
Sus scrofa
Description:
ChEMBL_541
Residue:
393
Sequence:
MTSYSDKGEKPERGRFLHFHSVTFWVGNAKQAASYYCSKIGFEPLAYKGLETGSREVVSHVVKQDKIVFVFSSALNPWNKEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAIIVREEVCCAADVRGHHTPLDRARQVWEGTLVEKMTFCLDSRPQPSQTLLHRLLLSKLPKCGLEIIDHIVGNQPDQEMESASQWYMRNLQFHRFWSVDDTQIHTEYSALRSVVMANYEESIKMPINEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRSLRERGVEFLAVPFTYYKQLQEKLKSAKIRVKESIDVLEELKILVDYDEKGYLLQIFTKPMQDRPTVFLEVIQRNNHQGFGAGNFNSLFKAFEEEQELRGNLTDTDPNGVPFRL
  
Inhibitor
Name:
BDBM50089165
Synonyms:
CHEMBL23622 | Cyclopropanecarboxylic acid 3-oxo-cyclohex-1-enyl ester
Type:
Small organic molecule
Emp. Form.:
C10H12O3
Mol. Mass.:
180.2005
SMILES:
O=C(OC1=CC(=O)CCC1)C1CC1 |t:3|
Structure:
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