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Target
N-methyl-D-aspartate receptor
Ligand
BDBM50079387
Substrate
n/a
Meas. Tech.
ChEMBL_141415 (CHEMBL751709)
IC50
11300±n/a nM
Citation
 Pabel, J; Höfner, G; Wanner, KT Synthesis and resolution of racemic eliprodil and evaluation of the enantiomers of eliprodil as NMDA receptor antagonists. Bioorg Med Chem Lett 10:1377-80 (2000) [PubMed]  Article 
Target
Name:
N-methyl-D-aspartate receptor
Synonyms:
Glutamate (NMDA) receptor subunit zeta 1
Type:
PROTEIN
Mol. Mass.:
27123.62
Organism:
Sus scrofa
Description:
ChEMBL_141416
Residue:
243
Sequence:
TAGFYRIPVLGLTTRMSIYSDKSIHLSFLRTVPPYSHQSSVWFEMMRVYSWNHIILLVSDDHEGRAARKRLETLLEERESKAEKVLQFDPGTKNVTALLMEARELEARVIILSASEDDAATVYRAAAMLNMTGSGYVWLVGEREISGNALRYAPDGIIGLQLINGKNESAHISDAVGVVAQAVHELLEKENITEPPRGCVGNTNIWKTGPLFKRVLMSSKYADGVTGRVEFNKDGDRKFANYS
  
Inhibitor
Name:
BDBM50079387
Synonyms:
1-(4-Chloro-phenyl)-2-[4-(4-fluoro-benzyl)-piperidin-1-yl]-ethanol | CHEMBL28564 | Eliprodil
Type:
Small organic molecule
Emp. Form.:
C20H23ClFNO
Mol. Mass.:
347.854
SMILES:
OC(CN1CCC(Cc2ccc(F)cc2)CC1)c1ccc(Cl)cc1
Structure:
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