Target
Erythropoietin receptor
Ligand
BDBM50091848
Substrate
n/a
Meas. Tech.
ChEBML_67869
IC50
85000±n/a nM
Citation
 Connolly, PJWetter, SKMurray, WVJohnson, DLMcMahon, FJFarrell, FXTullai, JJolliffe, LK Synthesis and erythropoietin receptor binding affinities of N,N-disubstituted amino acids. Bioorg Med Chem Lett 10:1995-9 (2001) [PubMed]  Article 
Target
Name:
Erythropoietin receptor
Synonyms:
EPO-R | EPOR | EPOR_HUMAN
Type:
PROTEIN
Mol. Mass.:
55040.56
Organism:
Homo sapiens (Human)
Description:
ChEMBL_67864
Residue:
508
Sequence:
MDHLGASLWPQVGSLCLLLAGAAWAPPPNLPDPKFESKAALLAARGPEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRYEVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPSDLDPLILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVGSEHAQDTYLVLDKWLLPRNPPSEDLPGPGGSVDIVAMDEGSEASSCSSALASKPSPEGASAASFEYTILDPSSQLLRPWTLCPELPPTPPHLKYLYLVVSDSGISTDYSSGDSQGAQGGLSDGPYSNPYENSLIPAAEPLPPSYVACS
  
Inhibitor
Name:
BDBM50091848
Synonyms:
CHEMBL59107 | {Bis-[(E)-3-(3-phenoxy-phenyl)-allyl]-amino}-acetic acid
Type:
Small organic molecule
Emp. Form.:
C32H29NO4
Mol. Mass.:
491.577
SMILES:
OC(=O)CN(C\C=C\c1cccc(Oc2ccccc2)c1)C\C=C\c1cccc(Oc2ccccc2)c1
Structure:
Search PDB for entries with ligand similarity: