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Reaction Details
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TargetMelatonin receptor
LigandBDBM50093271
Substrate/Competitorn/a
Meas. Tech.ChEMBL_104944
Ki 0.95±n/a nM
Citation Jellimann, CMathé-Allainmat, MAndrieux, JKloubert, SBoutin, JANicolas, JPBennejean, CDelagrange, PLanglois, M Synthesis of phenalene and acenaphthene derivatives as new conformationally restricted ligands for melatonin receptors. J Med Chem43:4051-62 (2000) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Melatonin receptor
Name:Melatonin receptor
Synonyms:MTNR1A | MTNR1A protein | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:Enzyme
Mol. Mass.:39392.94
Organism:Homo sapiens (Human)
Description:P48039
Residue:350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50093271
NameBDBM50093271
Synonyms:CHEMBL130876 | Cyclopropanecarboxylic acid (4-methoxy-2,3-dihydro-1H-phenalen-1-ylmethyl)-amide
TypeSmall organic molecule
Emp. Form.C19H21NO2
Mol. Mass.295.3755
SMILESCOc1ccc2cccc3C(CNC(=O)C4CC4)CCc1c23
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a