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Reaction Details
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TargetMelatonin receptor
LigandBDBM50093271
Substrate/Competitorn/a
Meas. Tech.ChEMBL_105244
Ki 0.79±n/a nM
Citation Jellimann, CMathé-Allainmat, MAndrieux, JKloubert, SBoutin, JANicolas, JPBennejean, CDelagrange, PLanglois, M Synthesis of phenalene and acenaphthene derivatives as new conformationally restricted ligands for melatonin receptors. J Med Chem43:4051-62 (2000) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Melatonin receptor
Name:Melatonin receptor
Synonyms:MTNR1B | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:Enzyme
Mol. Mass.:40203.54
Organism:Homo sapiens (Human)
Description:P49286
Residue:362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
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  Blast E-value cutoff:
BDBM50093271
NameBDBM50093271
Synonyms:CHEMBL130876 | Cyclopropanecarboxylic acid (4-methoxy-2,3-dihydro-1H-phenalen-1-ylmethyl)-amide
TypeSmall organic molecule
Emp. Form.C19H21NO2
Mol. Mass.295.3755
SMILESCOc1ccc2cccc3C(CNC(=O)C4CC4)CCc1c23
Structure
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n/a