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Target
C-C chemokine receptor type 1
Ligand
BDBM50098635
Substrate
n/a
Meas. Tech.
ChEMBL_218695 (CHEMBL821481)
IC50
2500±n/a nM
Citation
 Naya, A; Sagara, Y; Ohwaki, K; Saeki, T; Ichikawa, D; Iwasawa, Y; Noguchi, K; Ohtake, N Design, synthesis, and discovery of a novel CCR1 antagonist. J Med Chem 44:1429-35 (2001) [PubMed]  Article 
Target
Name:
C-C chemokine receptor type 1
Synonyms:
C-C CKR-1 | CC-CKR-1 | CCR-1 | CCR1_MOUSE | CD_antigen=CD191 | Ccr1 | Cmkbr1 | MIP-1alpha-R | Macrophage inflammatory protein 1-alpha receptor | RANTES-R
Type:
PROTEIN
Mol. Mass.:
40904.59
Organism:
Mus musculus
Description:
ChEMBL_1452291
Residue:
355
Sequence:
MEISDFTEAYPTTTEFDYGDSTPCQKTAVRAFGAGLLPPLYSLVFIIGVVGNVLVILVLMQHRRLQSMTSIYLFNLAVSDLVFLFTLPFWIDYKLKDDWIFGDAMCKLLSGFYYLGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGIITSIITWALAILASMPALYFFKAQWEFTHRTCSPHFPYKSLKQWKRFQALKLNLLGLILPLLVMIICYAGIIRILLRRPSEKKVKAVRLIFAITLLFFLLWTPYNLSVFVSAFQDVLFTNQCEQSKQLDLAMQVTEVIAYTHCCVNPIIYVFVGERFWKYLRQLFQRHVAIPLAKWLPFLSVDQLERTSSISPSTGEHELSAGF
  
Inhibitor
Name:
BDBM50098635
Synonyms:
2,7-Dibromo-9H-xanthene-9-carboxylic acid (1-cyclooct-1-enylmethyl-piperidin-4-yl)-amide | CHEMBL33580
Type:
Small organic molecule
Emp. Form.:
C28H32Br2N2O2
Mol. Mass.:
588.374
SMILES:
Brc1ccc2Oc3ccc(Br)cc3C(C(=O)NC3CCN(C\C4=C\CCCCCC4)CC3)c2c1 |t:23|
Structure:
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