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Target
D(1B) dopamine receptor
Ligand
BDBM85093
Substrate
n/a
Meas. Tech.
ChEBML_61336
Ki
>10000±n/a nM
Citation
 Huang, Y; Kegeles, LS; Bae, S; Hwang, D; Roth, BL; Savage, JE; Laruelle, M Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. Bioorg Med Chem Lett 11:1375-7 (2001) [PubMed]  Article 
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(1B) dopamine receptor | DOPAMINE D5 | DRD5_RAT | Dopamine D1B | Dopamine D5 receptor | Dopamine receptor | Drd5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52827.88
Organism:
RAT
Description:
Dopamine D1B 0 RAT::P25115
Residue:
475
Sequence:
MLPPGRNRTAQPARLGLQRQLAQVDAPAGSATPLGPAQVVTAGLLTLLIVWTLLGNVLVCAAIVRSRHLRAKMTNIFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGTFCDIWVAFDIMCSTASILNLCIISVDRYWAISRPFRYERKMTQRVALVMVGLAWTLSILISFIPVQLNWHRDKAGSQGQEGLLSNGTPWEEGWELEGRTENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSRGAYEPDPSLRASIKKETKVFKTLSMIMGVFVCCWLPFFILNCMVPFCSSGDAEGPKTGFPCVSETTFDIFVWFGWANSSLNPIIYAFNADFRKVFAQLLGCSHFCFRTPVQTVNISNELISYNQDTVFHKEIATAYVHMIPNAVSSGDREVGEEEEEGPFDHMSQISPTTPDGDLAAESVWELDCEEEVSLGKISPLTPNCFDKTA
  
Inhibitor
Name:
BDBM85093
Synonyms:
CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870 | NSC_3853
Type:
Small organic molecule
Emp. Form.:
C18H19ClN4
Mol. Mass.:
326.823
SMILES:
Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1
Structure:
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