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Target
Somatostatin receptor type 1
Ligand
BDBM50100750
Substrate
n/a
Meas. Tech.
ChEMBL_200539 (CHEMBL805043)
IC50
5.4±n/a nM
Citation
 Rivier, JE; Hoeger, C; Erchegyi, J; Gulyas, J; DeBoard, R; Craig, AG; Koerber, SC; Wenger, S; Waser, B; Schaer, JC; Reubi, JC Potent somatostatin undecapeptide agonists selective for somatostatin receptor 1 (sst1). J Med Chem 44:2238-46 (2001) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 1
Synonyms:
SOMATOSTATIN SST1 | SRIF-2 | SS-1-R | SS1-R | SS1R | SSR1_HUMAN | SSTR1 | Somatostatin receptor type 1 (SSTR1)
Type:
Enzyme
Mol. Mass.:
42692.81
Organism:
Homo sapiens (Human)
Description:
P30872
Residue:
391
Sequence:
MFPNGTASSPSSSPSPSPGSCGEGGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGVFRNGTCTSRITTL
  
Inhibitor
Name:
BDBM50100750
Synonyms:
CHEMBL410824 | Des-AA1,2-[DTrp8]-SRIF
Type:
Small organic molecule
Emp. Form.:
C71H96N16O17S2
Mol. Mass.:
1509.749
SMILES:
C[C@@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSCC(NC(=O)[C@H](CO)NC(=O)[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H](C)O)C(O)=O
Structure:
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