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Target3-dehydroquinate synthase
LigandBDBM50100860
Substrate/Competitorn/a
Meas. Tech.ChEMBL_350
Ki 21000±n/a nM
Citation Chandran, SSFrost, JW Aromatic inhibitors of dehydroquinate synthase: synthesis, evaluation and implications for gallic acid biosynthesis. Bioorg Med Chem Lett11:1493-6 (2001) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
3-dehydroquinate synthase
Name:3-dehydroquinate synthase
Synonyms:n/a
Type:Enzyme
Mol. Mass.:38878.02
Organism:Escherichia coli (strain K12)
Description:P07639
Residue:362
Sequence:
MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTNETLAPLYLDKVRGVLEQA
GVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVALGGGVVGDLTGFAAASYQR
GVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPPRELAS
GLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADERETGLR
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFSSAETQRIITLLKRA
GLPVNGPREMSAQAYLPHMLRDKKVLAGEMRLILPLAIGKSEVRSGVSHELVLNAIADCQ
SA
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BDBM50100860
NameBDBM50100860
Synonyms:3,4-Dihydroxy-5-phosphonomethyl-benzoic acid | CHEMBL289281
TypeSmall organic molecule
Emp. Form.C8H9O7P
Mol. Mass.248.1266
SMILESOC(=O)c1cc(O)c(O)c(CP(O)(O)=O)c1
Structure
n/a