Reaction Details Report a problem with these data
Target
Calpain small subunit 1
Ligand
BDBM50101319
Substrate
n/a
Meas. Tech.
ChEBML_43685
Ki
76000±n/a nM
Citation
 Donkor, IO; Zheng, X; Han, J; Lacy, C; Miller, DD Significance of hydrogen bonding at the S(1)' subsite of calpain I. Bioorg Med Chem Lett 11:1753-5 (2001) [PubMed]  Article 
Target
Name:
Calpain small subunit 1
Synonyms:
CANP small subunit | CAPN4 | CAPNS1 | CDPS | CPNS1_PIG | CSS1 | Calcium-activated neutral proteinase small subunit | Calcium-dependent protease small subunit | Calcium-dependent protease small subunit 1 | Calpain regulatory subunit
Type:
PROTEIN
Mol. Mass.:
28062.13
Organism:
Sus scrofa
Description:
ChEMBL_43862
Residue:
266
Sequence:
MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGTAMRILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKKWQAIYKQFDVDRSGTIGSSELPGAFEAAGFHLNEHLYSMIIRRYSDEGGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS
  
Inhibitor
Name:
BDBM50101319
Synonyms:
CHEMBL49829 | [(S)-1-((S)-1-Benzyl-2-diethylcarbamoyl-2-oxo-ethylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester
Type:
Small organic molecule
Emp. Form.:
C28H37N3O5
Mol. Mass.:
495.6105
SMILES:
CCN(CC)C(=O)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1
Structure:
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