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Target
Glucose-6-phosphatase catalytic subunit 1
Ligand
BDBM50103116
Substrate
n/a
Meas. Tech.
ChEBML_71686
IC50
>50000±n/a nM
Citation
 Madsen, P; Jakobsen, P; Westergaard, N N,N-dibenzyl-N'-benzylidenehydrazines: potent competitive glucose-6-phosphatase catalytic enzyme inhibitors. Bioorg Med Chem Lett 11:2165-7 (2001) [PubMed]  Article 
Target
Name:
Glucose-6-phosphatase catalytic subunit 1
Synonyms:
G6PC | G6PC1 | G6PC1_HUMAN | G6PT | Glucose-6-phosphatase
Type:
PROTEIN
Mol. Mass.:
40493.62
Organism:
Homo sapiens (Human)
Description:
ChEMBL_501266
Residue:
357
Sequence:
MEEGMNVLHDFGIQSTHYLQVNYQDSQDWFILVSVIADLRNAFYVLFPIWFHLQEAVGIKLLWVAVIGDWLNLVFKWILFGQRPYWWVLDTDYYSNTSVPLIKQFPVTCETGPGSPSGHAMGTAGVYYVMVTSTLSIFQGKIKPTYRFRCLNVILWLGFWAVQLNVCLSRIYLAAHFPHQVVAGVLSGIAVAETFSHIHSIYNASLKKYFLITFFLFSFAIGFYLLLKGLGVDLLWTLEKAQRWCEQPEWVHIDTTPFASLLKNLGTLFGLGLALNSSMYRESCKGKLSKWLPFRLSSIVASLVLLHVFDSLKPPSQVELVFYVLSFCKSAVVPLASVSVIPYCLAQVLGQPHKKSL
  
Inhibitor
Name:
BDBM50103116
Synonyms:
CHEMBL68981 | N,N-Dibenzyl-N'-[6-methoxy-3,4-dihydro-2H-naphthalen-(1E)-ylidene]-hydrazine
Type:
Small organic molecule
Emp. Form.:
C25H26N2O
Mol. Mass.:
370.4867
SMILES:
COc1ccc2C(CCCc2c1)=NN(Cc1ccccc1)Cc1ccccc1 |w:12.14|
Structure:
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