Reaction Details Report a problem with these data
Target
P2Y purinoceptor 1
Ligand
BDBM50104021
Substrate
n/a
Meas. Tech.
ChEMBL_147893 (CHEMBL759293)
IC50
1900±n/a nM
Citation
 Kim, HS; Barak, D; Harden, TK; Boyer, JL; Jacobson, KA Acyclic and cyclopropyl analogues of adenosine bisphosphate antagonists of the P2Y1 receptor: structure-activity relationships and receptor docking. J Med Chem 44:3092-108 (2001) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 1
Synonyms:
P2RY1 | P2RY1_MELGA
Type:
n/a
Mol. Mass.:
41199.64
Organism:
Meleagris gallopavo
Description:
n/a
Residue:
362
Sequence:
MTEALISAALNGTQPELLAGGWAAGNASTKCSLTKTGFQFYYLPTVYILVFITGFLGNSVAIWMFVFHMRPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDVMCKLQRFIFHVNLYGSILFLTCISVHRYTGVVHPLKSLGRLKKKNAVYVSSLVWALVVAVIAPILFYSGTGVRRNKTITCYDTTADEYLRSYFVYSMCTTVFMFCIPFIVILGCYGLIVKALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYLPFHVMKTLNLRARLDFQTPQMCAFNDKVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKSSRRSEPNVQSKSEEMTLNILTEYKQNGDTSL
  
Inhibitor
Name:
BDBM50104021
Synonyms:
CHEMBL104752 | Phosphoric acid mono-[2-(2-chloro-6-methylamino-purin-9-ylmethyl)-1-phosphonooxymethyl-cyclopropylmethyl] ester
Type:
Small organic molecule
Emp. Form.:
C12H18ClN5O8P2
Mol. Mass.:
457.701
SMILES:
CNc1nc(Cl)nc2n(CC3CC3(COP(O)(O)=O)COP(O)(O)=O)cnc12
Structure:
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