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Target
Motilin receptor
Ligand
BDBM50108829
Substrate
n/a
Meas. Tech.
ChEMBL_122666 (CHEMBL732796)
IC50
33±n/a nM
Citation
 Haramura, M; Okamachi, A; Tsuzuki, K; Yogo, K; Ikuta, M; Kozono, T; Takanashi, H; Murayama, E Design and synthesis of motilin antagonists derived from the [1-4] fragment of porcine motilin. J Med Chem 45:670-5 (2002) [PubMed]  Article 
Target
Name:
Motilin receptor
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
43771.25
Organism:
Oryctolagus cuniculus
Description:
n/a
Residue:
400
Sequence:
MGSPWNGSDGPEDAREPPWAALPPCDERRCSPFPLGTLVPVTAVCLGLFAVGVSGNVVTVLLIGRYRDMRTTTNLYLGSMAVSDLLILLGLPFDLYRLWRSRPWVFGQLLCRLSLYVGEGCTYASLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAALWAVALLSAGPFFFLVGVEQDPAVFAAPDRNGTVPLDPSSPAPASPPSGPGAEAAALFSRECRPSRAQLGLLRVMLWVTTAYFFLPFLCLSILYGLIARQLWRGRGPLRGPAATGRERGHRQTVRVLLVVVLAFIVCWLPFHVGRIIYINTQDSRMMYFSQYFNIVALQLFYLSASINPILYNLISKKYRAAARRLLRESRAGPSGVCGSRGPEQDVAGDTGGDTAGCTETSANTKTAA
  
Inhibitor
Name:
BDBM50108829
Synonyms:
2-Amino-N-[2-(3-tert-butyl-4-hydroxy-benzyl)-3,8,15-trioxo-1,4,9triaza-cyclopentadec-14-yl]-3-phenyl-propionamide | CHEMBL348744
Type:
Small organic molecule
Emp. Form.:
C32H45N5O5
Mol. Mass.:
579.7302
SMILES:
CC(C)(C)c1cc(CC2NC(=O)C(CCCCNC(=O)CCCNC2=O)NC(=O)C(N)Cc2ccccc2)ccc1O
Structure:
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