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Target
DNA polymerase beta
Ligand
BDBM50109029
Substrate
n/a
Meas. Tech.
ChEMBL_50296 (CHEMBL660416)
Ki
12800±n/a nM
Citation
 Watanabe, M; Hanashima, S; Mizushina, Y; Yoshida, H; Oshige, M; Sakaguchi, K; Sugawara, F Biotinylated lithocholic acids for affinity chromatography of mammalian DNA polymerases alpha and beta. Bioorg Med Chem Lett 12:287-90 (2002) [PubMed]  Article 
Target
Name:
DNA polymerase beta
Synonyms:
DNA Polymerase beta | DPOLB_RAT | Polb
Type:
PROTEIN
Mol. Mass.:
38334.34
Organism:
Rattus norvegicus
Description:
ChEMBL_1361926
Residue:
335
Sequence:
MSKRKAPQETLNGGITDMLVELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVTGIGPSAARKLVDEGIKTLEDLRKNEDKLNHHQRIGLKYFEDFEKRIPREEMLQMQDIVLNEVKKLDPEYIATVCGSFRRGAESSGDMDVLLTHPNFTSESSKQPKLLHRVVEQLQKVRFITDTLSKGETKFMGVCQLPSENDENEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEQDIFDYIQWRYREPKDRSE
  
Inhibitor
Name:
BDBM50109029
Synonyms:
4-{10,13-Dimethyl-3-[3-(6-{6-[5-(2-oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoylamino]-hexanoylamino}-hexanoylamino)-propionyloxy]-hexadecahydro-cyclopenta[a]phenanthren-17-yl}-pentanoic acid | CHEMBL3137892
Type:
Small organic molecule
Emp. Form.:
C49H81N5O8S
Mol. Mass.:
900.261
SMILES:
[H][C@@](C)(CCC(O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CCC4C[C@H](CC[C@]4(C)[C@@]3([H])CC[C@]12C)OC(=O)CCNC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCCC1SCC2NC(=O)NC12
Structure:
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