Target
Melanocyte-stimulating hormone receptor
Ligand
BDBM50111166
Substrate
n/a
Meas. Tech.
ChEBML_105844
Ki
>1000000±n/a nM
Citation
 Mutulis, FMutule, ILapins, MWikberg, JE Reductive amination products containing naphthalene and indole moieties bind to melanocortin receptors. Bioorg Med Chem Lett 12:1035-8 (2002) [PubMed]  Article 
Target
Name:
Melanocyte-stimulating hormone receptor
Synonyms:
MC1-R | MC1R | MSH-R | MSHR | MSHR_HUMAN | Melanocortin MC1 | Melanocortin receptor (M1 and M4) | Melanocortin receptor 1 (MC-1) | Melanocortin receptor 1 (MC1-R) | Melanocortin receptor 1 (MC1R)
Type:
Enzyme
Mol. Mass.:
34717.23
Organism:
Homo sapiens (Human)
Description:
Q01726
Residue:
317
Sequence:
MAVQGSQRRLLGSLNSTPTAIPQLGLAANQTGARCLEVSISDGLFLSLGLVSLVENALVVATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEAGALVARAAVLQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVVFSTLFIAYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPVHQGFGLKGAVTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICNAIIDPLIYAFHSQELRRTLKEVLTCSW
  
Inhibitor
Name:
BDBM50111166
Synonyms:
1-Naphthalen-2-ylmethyl-piperazine | CHEMBL8756
Type:
Small organic molecule
Emp. Form.:
C15H18N2
Mol. Mass.:
226.3168
SMILES:
C(N1CCNCC1)c1ccc2ccccc2c1
Structure:
Search PDB for entries with ligand similarity: